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At the cutting edge of innovation for the last 3 decades, Dr. Jamshid Maddahi has consistently contributed to and led research efforts in cardiovascular care and medical imaging. He has conducted cardiology research projects and prepared their findings for the medical community for the benefit of everyone potentially afflicted with related illness situation. See a summary of his efforts below to get more information on the ground breaking work of Dr. Jamshid Maddahi, as a researcher.

Dr. Maddahi's Publications

Dr. Jamshid Maddahi has authored more than 200 original publications, abstracts and book chapters. For these contributions, Dr. Maddahi has received numerous national and international awards from medical societies.

AURORA (International Study to Evaluate Diagnostic Efficacy of Flurpiridaz Injection PET MPI in the Detection of Coronary Artery Disease trial were published. The authors, led by Jamshid Maddahi, MD, FASNC, reported that PET imaging with flurpiridaz significantly exceeded prespecified threshold criteria for detection of CAD and was superior to Tc-labeled SPECT myocardial perfusion imaging for detection of CAD in the overall population and in women and obese patients.

Berman DS, Maddahi J, Tamarappoo BK, Czernin J, Taillefer R, Udelson JE, Gibson CM, Devine M, Lazewatsky J, Bhat G, Washburn D. Phase II safety and clinical comparison with single-photon emission computed tomography myocardial perfusion imaging for detection of coronary artery disease: flurpiridaz F 18 positron emission tomography. J Am Coll Cardiol. 2013 Jan 29;61(4):469-77. doi: 10.1016/j.jacc.2012.11.022. Epub 2012 Dec 19. PubMed PMID: 23265345.

Branscomb E, Heller G, Bateman T, Soman P, Maddahi J, Garcia E, Berman D, DePuey G. Advances in cardiac imaging: taking a closer look at PET perfusion imaging : American Society of Nuclear Cardiology, Philadelphia, PA, 24 September 2010. J Nucl Cardiol. 2012 Feb;19 Suppl 1:S46-7. doi: 10.1007/s12350-011-9489-2. PubMed PMID: 22147619.

Hendel RC, Abbott BG, Bateman TM, Blankstein R, Calnon DA, Leppo JA, Maddahi J, Schumaecker MM, Shaw LJ, Ward RP, Wolinsky DG; American Society of Nuclear Cardiology. The role of radionuclide myocardial perfusion imaging for asymptomatic individuals. J Nucl Cardiol. 2011 Feb;18(1):3-15. doi: 10.1007/s12350-010-9320-5. PubMed PMID: 21181519.

Bai C, Conwell R, Kindem J, Babla H, Gurley M, De Los Santos R 2nd, Old R, Weatherhead R, Arram S, Maddahi J. Phantom evaluation of a cardiac SPECT/VCT system that uses a common set of solid-state detectors for both emission and transmission scans. J Nucl Cardiol. 2010 Jun;17(3):459-69. doi: 10.1007/s12350-010-9204-8. Epub 2010 Feb 19. PubMed PMID: 20169476; PubMed Central PMCID: PMC2866957.

Maddahi J. Properties of an ideal PET perfusion tracer: new PET tracer cases and data. J Nucl Cardiol. 2012 Feb;19 Suppl 1:S30-7. doi: 10.1007/s12350-011-9491-8. Review. PubMed PMID: 22259007.

Maddahi J, Czernin J, Lazewatsky J, Huang SC, Dahlbom M, Schelbert H, Sparks R, Ehlgen A, Crane P, Zhu Q, Devine M, Phelps M. Phase I, first-in-human study of BMS747158, a novel 18F-labeled tracer for myocardial perfusion PET: dosimetry, biodistribution, safety, and imaging characteristics after a single injection at rest. J Nucl Med. 2011 Sep;52(9):1490-8. doi: 10.2967/jnumed.111.092528. Epub 2011 Aug 17. PubMed PMID: 21849402.

Thomas GS, Maddahi J. The technetium shortage. J Nucl Cardiol. 2010 Dec;17(6):993-8. doi: 10.1007/s12350-010-9281-8. PubMed PMID: 20717761.

Maddahi J. Viability assessment with MRI is superior to FDG-PET for viability: Pro. J Nucl Cardiol. 2010 Apr;17(2):292-7. doi: 10.1007/s12350-010-9201-y. PubMed PMID: 20225004.

Di Carli MF, Asgarzadie F, Schelbert HR, Brunken RC, Laks H, Phelps ME, Maddahi J. Quantitative relation between myocardial viability and improvement in heart failure symptoms after revascularization in patients with ischemic cardiomyopathy. Circulation. 1995 Dec 15;92(12):3436-44. PubMed PMID: 8521565.

Maddahi J, Berman DS. Reverse redistribution of thallium-201. J Nucl Med. 1995 Jun;36(6):1019-21. PubMed PMID: 7769420.

Yao WJ, Hoh CK, Hawkins RA, Glaspy JA, Weil JA, Lee SJ, Maddahi J, Phelps ME. Quantitative PET imaging of bone marrow glucose metabolic response to hematopoietic cytokines. J Nucl Med. 1995 May;36(5):794-9. PubMed PMID: 7738650.

Ritchie JL, Gibbons RJ, Johnson LL, Maddahi J, Schelbert HR, Wackers FJ, Zaret BL. Guidelines for training in adult cardiovascular medicine. Core Cardiology Training Symposium (COCATS). Task Force 5: training in nuclear cardiology. American College of Cardiology and the American Society of Nuclear Cardiology. J Nucl Cardiol. 1995 Mar-Apr;2(2 Pt 1):167-71. PubMed PMID: 9463027.

Palmas W, Bingham S, Diamond GA, Denton TA, Kiat H, Friedman JD, Scarlata D, Maddahi J, Cohen I, Berman DS. Incremental prognostic value of exercise thallium-201 myocardial single-photon emission computed tomography late after coronary artery bypass surgery. J Am Coll Cardiol. 1995 Feb;25(2):403-9. PubMed PMID: 7829794.

Ritchie JL, Gibbons RJ, Johnson LL, Maddahi J, Schelbert HR, Wackers FJ, Zaret BL. Guidelines for training in adult cardiovascular medicine. Core Cardiology Training Symposium (COCATS). Task Force 5: training in nuclear cardiology. J Am Coll Cardiol. 1995 Jan;25(1):19-23. PubMed PMID: 7798500.

Schelbert HR, Maddahi J. Clinical cardiac PET: quo vadis? J Nucl Cardiol. 1994 Nov-Dec;1(6):576-9. PubMed PMID: 9420753.

Maddahi J. Clinical applications of antimyosin monoclonal antibody imaging. Am J Card Imaging. 1994 Jul;8(3):249-60. Review. PubMed PMID: 7950176.

Berman DS, Kiat H, Maddahi J. The new 99mTc myocardial perfusion imaging agents: 99mTc-sestamibi and 99mTc-teboroxime. Circulation. 1991 Sep;84(3 Suppl):I7-21. Review. PubMed PMID: 1832100.

Hawkins RA, Hoh C, Dahlbom M, Choi Y, Glaspy J, Tse N, Slamon D, Chen B, Messa C, Maddahi J, et al. PET cancer evaluations with FDG. J Nucl Med. 1991 Aug;32(8):1555-8. PubMed PMID: 1869978.

Berman DS, Kiat H, Van Train K, Garcia E, Friedman J, Maddahi J. Technetium 99m sestamibi in the assessment of chronic coronary artery disease. Semin Nucl Med. 1991 Jul;21(3):190-212. Review. PubMed PMID: 1835137.

Maddahi J, Kiat H, Berman DS. Myocardial perfusion imaging with technetium-99m-labeled agents. Am J Cardiol. 1991 May 21;67(14):27D-34D. Review. PubMed PMID: 1827941.

Matzer L, Kiat H, Friedman JD, Van Train K, Maddahi J, Berman DS. A new approach to the assessment of tomographic thallium-201 scintigraphy in patients with left bundle branch block. J Am Coll Cardiol. 1991 May;17(6):1309-17. PubMed PMID: 2016448.

Chouraqui P, Maddahi J, Henkin R, Karesh SM, Galie E, Berman DS. Comparison of myocardial imaging with iodine-123-iodophenyl-9-methyl pentadecanoic acid and thallium-201-chloride for assessment of patients with exercise-induced myocardial ischemia. J Nucl Med. 1991 Mar;32(3):447-52. PubMed PMID: 2005454.

Kiat H, Van Train KF, Maddahi J, Corbett JR, Nichols K, McGhie AI, Akers MS, Friedman JD, Roy L, Berman DS. Development and prospective application of quantitative 2-day stress-rest Tc-99m methoxy isobutyl isonitrile SPECT for the diagnosis of coronary artery disease. Am Heart J. 1990 Dec;120(6 Pt 1):1255-66. PubMed PMID: 2248175.

Weiss AT, Berman DS, Lew AS, Nielsen J, Potkin B, Swan HJ, Waxman A, Maddahi J. Transient ischemic dilation of the left ventricle on stress thallium-201 scintigraphy: a marker of severe and extensive coronary artery disease. J Am Coll Cardiol. 1987 Apr;9(4):752-9. PubMed PMID: 3558976.

Prigent F, Maddahi J, Garcia EV, Resser K, Lew AS, Berman DS. Comparative methods for quantifying myocardial infarct size by thallium-201 SPECT. J Nucl Med. 1987 Mar;28(3):325-33. PubMed PMID: 3493334.

Prigent F, Maddahi J, Garcia EV, Satoh Y, Van Train K, Berman DS. Quantification of myocardial infarct size by thallium-201 single-photon emission computed tomography: experimental validation in the dog. Circulation. 1986 Oct;74(4):852-61. PubMed PMID: 2428540.

Shah PK, Maddahi J, Staniloff HM, Ellrodt AG, Pichler M, Swan HJ, Berman DS. Variable spectrum and prognostic implications of left and right ventricular ejection fractions in patients with and without clinical heart failure after acute myocardial infarction. Am J Cardiol. 1986 Sep 1;58(6):387-93. PubMed PMID: 3751905.

Reisman S, Maddahi J, Van Train K, Garcia E, Berman D. Quantitation of extent, depth, and severity of planar thallium defects in patients undergoing exercise thallium-201 scintigraphy. J Nucl Med. 1986 Aug;27(8):1273-81. PubMed PMID: 3734900.

Maddahi J, Berman D. Nuclear medicine: single-photon emission computed tomography using thallium 201 for evaluating coronary artery disease. West J Med. 1986 Feb;144(2):217-8. PubMed PMID: 18749924; PubMed Central PMCID: PMC1306571.

Gutman J, Rozanski A, Garcia E, Maddahi J, Miyamoto A, Berman D. Complementary roles of scintigraphic and angiographic techniques in assessment of the extent of coronary artery disease. Am Heart J. 1982 Sep;104(3):653-60. PubMed PMID: 7113911.

Rozanski A, Berman D, Gray R, Diamond G, Raymond M, Prause J, Maddahi J, Swan HJ, Matloff J. Preoperative prediction of reversible myocardial asynergy by postexercise radionuclide ventriculography. N Engl J Med. 1982 Jul 22;307(4):212-6. PubMed PMID: 6979708.

Bateman T, Gray R, Maddahi J, Rozanski A, Raymond M, Berman D. Transient appearance of Q waves in coronary disease during exercise electrocardiography: consideration of mechanisms and clinical importance. Am Heart J. 1982 Jul;104(1):182-4. PubMed PMID: 7090981.

Ganz W, Ninomiya K, Hashida J, Fishbein MC, Buchbinder N, Marcus H, Mondkar A, Maddahi J, Shah PK, Berman D, Charuzi Y, Geft I, Shell W, Swan HJ. Intracoronary thrombolysis in acute myocardial infarction: experimental background and clinical experience. Am Heart J. 1981 Dec;102(6 Pt 2):1145-9. PubMed PMID: 7315719.

Maddahi J, Garcia EV, Berman DS, Waxman A, Swan HJ, Forrester J. Improved noninvasive assessment of coronary artery disease by quantitative analysis of regional stress myocardial distribution and washout of thallium-201. Circulation. 1981 Nov;64(5):924-35. PubMed PMID: 7285307.

Rozanski A, Berman DS, Gray R, Levy R, Raymond M, Maddahi J, Pantaleo N, Waxman AD, Swan HJ, Matloff J. Use of thallium-201 redistribution scintigraphy in the preoperative differentiation of reversible and nonreversible myocardial asynergy. Circulation. 1981 Nov;64(5):936-44. PubMed PMID: 6974614.

Maddahi J, Ganz W, Ninomiya K, Hashida J, Fishbein MC, Mondkar A, Buchbinder N, Marcus H, Geft I, Shah PK, Rozanski A, Swan HJ, Berman DS. Myocardial salvage by intracoronary thrombolysis in evolving acute myocardial infarction: evaluation using intracoronary injection of thallium-201. Am Heart J. 1981 Oct;102(4):664-74. PubMed PMID: 6169270.

Freeman MR, Berman DS, Staniloff H, Elkayam U, Maddahi J, Swan HJ, Forrester J. Comparison of upright and supine bicycle exercise in the detection and evaluation of extent of coronary artery disease by equilibrium radionuclide ventriculography. Am Heart J. 1981 Aug;102(2):182-9. PubMed PMID: 7258091.

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